This is a featured article. Click here for what enzymes and proteins are involved in dna replication information. As a consequence, the DNA repair process is constantly active as it responds to damage in the DNA structure. The rate of DNA repair is dependent on many factors, including the cell type, the age of the cell, and the extracellular environment. The DNA repair ability of a cell is vital to the integrity of its genome and thus to the normal functionality of that organism.
DNA damage repair and protection. 10,000 to 1,000,000 molecular lesions per cell per biochemically significant enzymes are derived from. While this constitutes only 0. These modifications can in turn disrupt the molecules’ regular helical structure by introducing non-native chemical bonds or bulky adducts that do not fit in the standard double helix. The replication of damaged DNA before cell division can lead to the incorporation of wrong bases opposite damaged ones. DNA base is stitched into place in a newly forming DNA strand, or a DNA base is skipped over or mistakenly inserted.